Faculty
Faculty Network
We ensure that trainees are exposed to the breadth of biological approaches throughout their training years. To that end, there is a large network of UVA researchers from 3 schools and 10 departments to provide a comprehensive graduate training program in modern cell and molecular biological sciences. In addition there is a tremendous amount of collaboration among the CMB faculty as illustrated by the network of collaborative publications.
Faculty

Agaisse, Hervé
Genetic approaches, cellular and molecular biology of intracellular pathogen infection

Barrett, Paula Q.
Regulation of low-voltage activated T-type Ca2+ channel activity by kinases and heterotrimeric G-proteins and their roles in physiological responses.

Bekiranov, Stefan
Physical Modeling of Microarray Hybridization; Analysis of Genomic Tiling Array Data; Bioinformatics; Computational Biology; Regulatory Networks

Bushweller, John H.
Drug Development Targeting Transcription Drivers in Cancer; Structure/Function Studies of Transcription Factor Drivers in Cancer

Casanova, James E.
Role of Arf family GTPases in vesicular transport and cytoskeleton assembly.
Cell Biology of bacterial pathogenesis.
The innate immune response to bacterial infection.

Deppmann, Christopher
Elucidating and Understanding the Mechanisms Underlying Nervous System Development

DeSimone, Douglas W.
Cell Adhesion and Adhesion-Dependent Cell Signaling in Vertebrate Morphogenesis

Dutta, Anindya
Genomic Instability in Cancer Cells; Noncoding RNAs in differentiation and cancer; Bioinformatics of cancer outcome

Engelhard, Victor H.
Identification of MHC-restricted tumor antigens / Control of T cell homing to tumors / Tertiary lymphoid structures and intratumoral immunity

Guler, Jennifer
Mechanisms of Genetic and Metabolic Adaptation in the Malaria Parasite, Plasmodium falciparum

Hammarskjöld, Marie-Louise
Post Transcriptional Gene Regulation and the Molecular Biology of Human Retroviruses

Hirsh, Jay
Molecular genetics; development and function of neurotransmitter-synthesizing neurons in Drosophila

Holmes, Jeffrey W.
Healing after myocardial infarction, cardiac growth and remodeling, and image-based modeling and diagnosis.

Isakson, Brant
Translating our discoveries in the microcirculation to tangible benefits in patients.

Jiang, Hao
Regulation of stem cell function and tumorigenesis by epigenetics and biomolecular condensation (phase separation)

Kasson, Peter M.
Physical mechanisms of infectious disease; influenza infection; membrane fusion; antibiotic resistance; molecular dynamics simulation; machine learning.

Kelly, Kimberly
Advancement in the design of imaging agents; molecular imaging and radiological sciences.

Kucenas, Sarah C.
The role of glia in the development, maintenance and regeneration of the nervous system

Leitinger, Norbert
Role of lipid oxidation products in inflammation and vascular immunology in atherosclerosis and diabetes

Li, Hui
Gene regulation in cancer, RNA processing; Epigenetic modification; Stem cell and development

Lu, Xiaowei
Wnt/PCP signaling in inner ear development Mouse models for human deafness Wnt/PCP signaling in neural tube closure

Minor, Wladek
Structure-Function Relationships in Macromolecules; Infectious Diseases and Drug Discovery; Bioinformatics and Big Data; Scientific Reproducibility

Mohi, Golam
Cell signaling, stem cell biology, molecular and epigenetic mechanisms of blood and breast cancers

Owens, Gary K.
Identification of Factors and Mechanisms that Regulate the Stability of Late Stage Atherosclerotic Lesions and the Probability of Thromboembolic Events Including a Heart Attack or Stroke

Peirce-Cottler, Shayn M.
Tissue Engineering and Regeneration, Computational Systems Biology, Vascular Growth and Remodeling, Stem Cell Therapies

Perez-Reyes, Edward
Exploring epilepsy circuits then preventing seizures using gene therapies. Developing drug-inducible genetic switches for insulin replacement gene therapies.

Pornillos, Owen
Structure and assembly of HIV, virus/host interactions, structural biology of the innate immune system

Rekosh, David M.
Human Immunodeficiency Virus Gene Expression; Human Endogenous Viruses; SARS-CoV-2 Protein Trafficking; Post-transcriptional Gene Regulation

Saucerman, Jeffrey J.
Roles of complex signaling networks involved in the regulation of cardiovascular function and disease

Sheffield, Nathan
computational biology & bioinformatics; high performance computing; epigenomics & chromatin; pediatric cancer; computational regulatory genomics; machine learning

Stukenberg, P. Todd
Mechanisms of chromosome segregation in Mitosis and generation of Chromosomal Instability in tumors

Tamm, Lukas K.
Biomembrane Structure and Function; Cell Entry of Enveloped Viruses; Neurosecretion by Exocytosis; Structure of Bacterial Pathogen Membrane Proteins; Lipid-Protein Interactions

Thisse, Christine I.
Molecular Mechanisms of Early Vertebrate Development and Morphogenesis. Application to Stem Cell Biology and Regenerative Medicine

Venton, B. Jill
Analytical Neurochemistry; Dopamine and Serotonin Neurotransmission in Drosophila; Mechanisms of rapid adenosine signaling in rodents

Wiener, Michael C.
Structure/function of integral membrane proteins; structural biophysics; enzymology and virology of ZMPSTE24; sparse-constraint structure determination; technology development

Winckler, Bettina
Endosomal function and dysfunction in neurons. Development of the nervous system: cytoskeleton and membrane traffic in axon and dendrite growth.

Wotton, David
Regulation of Gene Expression, Development and Tumor Progression by TGF beta Signaling

Wu, Martin
Research: microbial evolution and ecology, microbial genomics, metagenomics, bioinformatics, phylogenomics, endosymbionts

Yeager, Mark
Cardiac Gap Junction Membrane Channels / Integrins Water Channels / Rotavirus / Reovirus / Retrovirus

Zang, Chongzhi
Bioinformatics methodology development; Epigenetics and chromatin biology; Transcriptional regulation; Cancer genomics and epigenomics; Statistical methods for biomedical data integration; Advanced machine learning; Theoretical and computational biophysic

Zimmer, Jochen
Transport of biopolymers across biological membranes with a particular interest in polysaccharide and protein translocation.