Faculty
Barrett, Paula Q.
Regulation of low-voltage activated T-type Ca2+ channel activity by kinases and heterotrimeric G-proteins and their roles in physiological responses.
Bekiranov, Stefan
Physical Modeling of Microarray Hybridization; Analysis of Genomic Tiling Array Data; Bioinformatics; Computational Biology; Regulatory Networks
Bushweller, John H.
Drug Development Targeting Transcription Drivers in Cancer; Structure/Function Studies of Transcription Factor Drivers in Cancer; Structural Studies of Membrane Proteins
Casanova, James E.
Role of Arf family GTPases in vesicular transport and cytoskeleton assembly.<br> Cell Biology of bacterial pathogenesis. <br>The innate immune response to bacterial infection.
Castle, J. David
Intracellular cholesterol and the regulation of insulin secretion and membrane trafficking.
Corwin, Jeffrey T.
Regeneration and Developmental Biology of the Hearing and Balance Organs in the Vertebrate Ear.
Deppmann, Christopher
Elucidating and Understanding the Mechanisms Underlying Nervous System Development
DeSimone, Douglas W.
Cell Adhesion and Adhesion-Dependent Cell Signaling in Vertebrate Morphogenesis
Engel, Daniel A.
Drug Discovery and Molecular Biology of Pathogenic RNA viruses: Influenza, Dengue and Ebola.
Engelhard, Victor H.
Identification of MHC-restricted tumor antigens / Control of T cell homing to tumors / Role of lymphatic endothelial cells in regulating immunity and self-tolerance
Erickson, Loren D.
Cellular and molecular mechanisms of B lymphocyte function; Genetic susceptibility in systemic lupus erythematosus; Immunotherapeutics in the treatment of B cell disorders
Grainger, Robert M.
Molecular embryology--gene regulation in cells committed to specific developmental lineages
Gumbiner, Barry M.
Cell Adhesion and Morphogenesis; Cancer mechanisms; Cadherins and catenins; Hippo signaling pathway
Hammarskjöld, Marie-Louise
Post Transcriptional Gene Regulation and the Molecular Biology of Human Retroviruses
Hirsh, Jay
Molecular genetics; development and function of neurotransmitter-synthesizing neurons in Drosophila
Holmes, Jeffrey W.
Healing after myocardial infarction, cardiac growth and remodeling, and image-based modeling and diagnosis.
Isakson, Brant
Translating our discoveries in the microcirculation to tangible benefits in patients.
Kasson, Peter M.
Mechanisms of cell entry by influenza; Viral glycan recognition; drug resistance; molecular dynamics simulation; distributed computing.
Keller, Susanna R.
Insulin signaling, insulin-regulated membrane trafficking and associated changes in cellular function and whole body physiology
Kelly, Kimberly
Advancement in the design of imaging agents; molecular imaging and radiological sciences.
Kipnis, Jonathan
Neuroimmunology and glia biology in cognition, neurodevelopment and neurodegeneration
Kucenas, Sarah C.
The role of glia in the development, maintenance and regeneration of the nervous system
Laurie, Gordon W.
Role of Prosecretory Mitogen 'Lacritin' in Epithelial Homeostasis, Secretion and Innate Defense
Leitinger, Norbert
Role of lipid oxidation products in inflammation and vascular immunology in atherosclerosis and diabetes
Li, Chien
Neuroendocrine regulation of energy balance and stress, regulation of pancreatic islet hormone secretion and glucose homeostasis
Li, Hui
Gene regulation in cancer, RNA processing; Epigenetic modification; Stem cell and development
Lorenz, Ulrike M
Involvement of the protein tyrosine phosphatase SHP-1 in signal transduction pathways
Minor, Wladek
Structure-Function Relationships in Macromolecules; Infectious Diseases and Drug Discovery; Bioinformatics and Big Data; Scientific Reproducibility
Owens, Gary K.
Identification of Factors and Mechanisms that Regulate the Stability of Late Stage Atherosclerotic Lesions and the Probability of Thromboembolic Events Including a Heart Attack or Stroke
Patel, Manoj
Modulation of sodium channel gating by beta subunits and novel sodium channel blockers; Synaptic transmission in dorsal horn neurons
Peirce-Cottler, Shayn M.
Tissue Engineering and Regeneration, Computational Systems Biology, Vascular Growth and Remodeling, Stem Cell Therapies
Perez-Reyes, Edward
Exploring epilepsy circuits then preventing seizures using AAV-based gene therapies.
Pfister, K. Kevin
Regulation of Cytoplasmic Dynein for Membrane Bounded Organelle Trafficking in Axons
Pornillos, Owen
Structure and assembly of HIV Virus/host interactions; Structural biology of the innate immune system
Provencio, Ignacio
The Role of Melanopsin Retinal Ganglion Cells in the Photic Regulation of Mammalian Circadian Rhythms
Quinlan, Aaron R.
Bioinformatics and computational genomics; Variation in genome structure; Somatic genome evolution; Cancer genome biology
Saucerman, Jeffrey J.
Roles of complex signaling networks involved in the regulation of cardiovascular function and disease
Siegrist, Sarah
Regulation of neural stem cell proliferation by extracellular factors, local and systemic. Intrinsic signaling programs regulating neural stem cell fate decisions: death versus survival. Functional and molecular similarities between Drosophila and mammal
Smith, M. Mitchell
Functional Genomics of Histones, Chromatin, and Protein Acetylation Signaling in Cancer and the Cell Cycle
Somlyo, Avril V.
Novel signal transduction pathways in smooth muscles that regulate contractility and impact diseases of the vasculature, airway and gastrointestinal tract.
Stukenberg, P. Todd
Mechanisms of chromosome segregation in Mitosis and generation of Chromosomal Instability in tumors
Tamm, Lukas K.
Biomembrane Structure and Function; Cell Entry of Enveloped Viruses; Neurosecretion by Exocytosis; Structure of Bacterial Pathogen Membrane Proteins; Lipid-Protein Interactions
Taylor, Angela M.
Diabetic cardiovascular disease - early diagnosis and prevention; Women's heart disease.
Thisse, Christine I.
Molecular Mechanisms of Early Vertebrate Development and Morphogenesis. Application to Stem Cell Biology and Regenerative Medicine
Venton, B. Jill
Analytical Neurochemistry; Dopamine and Serotonin Neurotransmission in Drosophila; Mechanisms of rapid adenosine signaling in rodents
Wiener, Michael C.
Structural biology (esp. crystallography) of integral membrane proteins; TonB-dependent active transport across the bacterial outer membrane; cancer-related membrane proteins; crystallization methods development
Winckler, Bettina
Endosomal function and dysfunction in neurons. Wiring the nervous system in development.
Wu, Martin
Research: microbial evolution and ecology, microbial genomics, metagenomics, bioinformatics, phylogenomics, endosymbionts
Wotton, David
Regulation of Gene Expression, Development and Tumor Progression by TGF beta Signaling
Yeager, Mark
Cardiac Gap Junction Membrane Channels / Integrins Water Channels / Rotavirus / Reovirus / Retrovirus
Zimmer, Jochen
Transport of biopolymers across biological membranes with a particular interest in polysaccharide and protein translocation.
