Faculty

Faculty Network

Collaborative connections with Cell and Molecular Biology researchers: Patrick Grant, Marty Mayo, Pierce-Cottier Shayn, Linda Columbus, Kevin Lynch, Jeffrey Saucerman, Kevin James, Jeffrey Smith, Sanchita Bhahtnager, Benjamin Purrow, Daniel Gioellii, Roger Abounder, Jason PippinWe ensure that trainees are exposed to the breadth of biological approaches throughout their training years. To that end, there is a large network of UVA researchers  from 3 schools and 10 departments to provide a comprehensive graduate training program in modern cell and molecular biological sciences. In addition there is a tremendous amount of collaboration among the CMB faculty as illustrated by the network of collaborative publications.

Faculty Network (PDF)
Color Legend (PDF)

Faculty
Roger Abounader

Abounader, Roger

Basic and translational brain tumor research

Herve Agaisse

Agaisse, Hervé

Genetic approaches, cellular and molecular biology of intracellular pathogen infection

David Auble

Auble, David T.

Molecular Mechanisms of Transcriptional Regulation

Paula Barrett

Barrett, Paula Q.

Regulation of low-voltage activated T-type Ca2+ channel activity by kinases and heterotrimeric G-proteins and their roles in physiological responses.

Douglas Bayliss

Bayliss, Douglas A.

Mechanisms of neuromodulation in central neurons

Mark Beenhakker

Beenhakker, Mark P.

Circuit mechanisms of sleep and epilepsy

Stefan Bekiranov

Bekiranov, Stefan

Physical Modeling of Microarray Hybridization; Analysis of Genomic Tiling Array Data; Bioinformatics; Computational Biology; Regulatory Networks

Sanchita Bhatnagar

Bhatnagar, Sanchita

Epigenetic Silencing Mechanisms-Implications in Breast Cancer and Rett Syndrome

George Bloom

Bloom, George S.

Pathogenic mechanisms in Alzheimer's Disease and other neurodegenerative disorders

Amy Bouton

Bouton, Amy H.

Signaling Pathways and Breast Cancer

John Bushweller

Bushweller, John H.

Drug Development Targeting Transcription Drivers in Cancer; Structure/Function Studies of Transcription Factor Drivers in Cancer

Steven Caliari

Caliari, Steven

Engineering dynamic biomaterials to explore the interplay between cells and their microenvironment

James Casanova

Casanova, James E.

Role of Arf family GTPases in vesicular transport and cytoskeleton assembly.
Cell Biology of bacterial pathogenesis.
The innate immune response to bacterial infection.

Mete Civelek

Civelek, Mete

Systems Genetics Approaches to Understand Cardiometabolic Traits

Anna Cliffe

Cliffe, Anna

Herpes Simplex Virus Infection of Neurons

Linda Columbus

Columbus, Linda

Biophysical Chemistry: Membrane protein structure, function, and dynamics

Jeffrey Corwin

Corwin, Jeffrey T.

Regeneration and Developmental Biology of the Hearing and Balance Organs in the Vertebrate Ear.

Alison Criss

Criss, Alison K.

Cellular and molecular mechanisms of Neisserial pathogenesis

Christopher Deppmann

Deppmann, Christopher

Elucidating and Understanding the Mechanisms Underlying Nervous System Development

Bimal Desai

Desai, Bimal N.

Ion channels and Ca2+-signaling in inflammation, immunity and tissue homeostasis

Douglas DeSimone

DeSimone, Douglas W.

Cell Adhesion and Adhesion-Dependent Cell Signaling in Vertebrate Morphogenesis

Anindya Dutta

Dutta, Anindya

Genomic Instability in Cancer Cells; Noncoding RNAs in differentiation and cancer

Noelle Dwyer

Dwyer, Noelle

Neural Development; Cell Division in Neural Stem Cells; Axon Outgrowth and Guidance

Edward Egelman

Egelman, Edward H.

Structure and Function of Macromolecular Complexes Using Electron Microscopy

Victor Engelhard

Engelhard, Victor H.

Identification of MHC-restricted tumor antigens / Control of T cell homing to tumors / Tertiary lymphoid structures and intratumoral immunity

Loren Erickson

Erickson, Loren D.

Immune mechanisms of pathogenic antibody production in allergy and autoimmunity

Charles Farber

Farber, Charles R.

Systems Genetics of Skeletal Development and Maintenance

Daniel Gioeli

Gioeli, Daniel

Signal transduction in cancer cells

Patrick Grant

Grant, Patrick A.

Transcription; Chromatin Modifications, Neurodegenerative Disease, Cancer

Michael Guertin

Guertin, Michael

Transcription, Chromatin, Cancer, Molecular Biology, Genomics, and Computational Biology

Jennifer Guler

Guler, Jennifer

Mechanisms of Genetic and Metabolic Adaptation in the Malaria Parasite, Plasmodium falciparum

Young Hahn

Hahn, Young S.

Immune regulation for HCV infection and chronic liver inflammation

Marie-Louise

Hammarskjöld, Marie-Louise

Post Transcriptional Gene Regulation and the Molecular Biology of Human Retroviruses

Jay Hirsh

Hirsh, Jay

Molecular genetics; development and function of neurotransmitter-synthesizing neurons in Drosophila

Jeffrey Holmes

Holmes, Jeffrey W.

Healing after myocardial infarction, cardiac growth and remodeling, and image-based modeling and diagnosis.

Brant Isakson

Isakson, Brant

Translating our discoveries in the microcirculation to tangible benefits in patients.

Kevin Janes

Janes, Kevin A.

Systems-biology approaches to cancer biology and virology.

Hao Jiang

Jiang, Hao

Regulation of stem cell function and tumorigenesis by epigenetics and biomolecular condensation (phase separation)

Jung-Bum Shin

Shin, Jung-Bum

Auditory Neurobiology

David Kashatus

Kashatus, David F

The Role of Mitochondrial Fusion and Fission in Tumorigenesis.

Peter Kasson

Kasson, Peter M.

Physical mechanisms of infectious disease; influenza infection; membrane fusion; antibiotic resistance; molecular dynamics simulation; machine learning.

Dean Kedes

Kedes, Dean H.

Human Herpes virus associated with malignancy, including Kaposi's Sarcoma

Kimberly Kelly

Kelly, Kimberly

Advancement in the design of imaging agents; molecular imaging and radiological sciences.

Anne Kenworthy

Kenworthy, Anne

Architecture and function of biological membranes

Mark Kester

Kester, Mark

Nanotechnologies for targeted drug delivery

Jonathan Kipnis

Kipnis, Jonathan

Neuroimmunology and glia biology in cognition, neurodevelopment and neurodegeneration

Sarah Kucenas

Kucenas, Sarah C.

The role of glia in the development, maintenance and regeneration of the nervous system

Gordon Laurie

Laurie, Gordon W.

Role of Prosecretory Mitogen 'Lacritin' in Epithelial Homeostasis, Secretion and Innate Defense

Norbert Leitinger

Leitinger, Norbert

Role of lipid oxidation products in inflammation and vascular immunology in atherosclerosis and diabetes

Hui Li

Li, Hui

Gene regulation in cancer, RNA processing; Epigenetic modification; Stem cell and development

Xiaowei Lu

Lu, Xiaowei

Developmental regulation of planar cell polarity in the mammalian nervous system

Kevin Lynch

Lynch, Kevin R.

Chemical biology of sphingosine 1-phosphate

Mani Mahadevan

Mahadevan, Mani S.

Molecular Mechanisms of Myotonic Muscular Dystrophy

Marty Mayo

Mayo, Marty W.

Transcriptional Regulation by NFKB

Wladek Minor

Minor, Wladek

Structure-Function Relationships in Macromolecules; Infectious Diseases and Drug Discovery; Bioinformatics and Big Data; Scientific Reproducibility

Golam Mohi

Mohi, Golam

Cell signaling, hematopoietic stem cell biology, molecular and epigenetic mechanisms of leukemia.

Eyleen O'Rourke

O’Rourke, Eyleen Jorgelina

Obesity and Aging

Gary Owens

Owens, Gary K.

Identification of Factors and Mechanisms that Regulate the Stability of Late Stage Atherosclerotic Lesions and the Probability of Thromboembolic Events Including a Heart Attack or Stroke

Jason Papin

Papin, Jason A.

Systems biology, infectious disease, cancer, toxicology, metabolic engineering

Kwon-Sik Park

Park, Kwon-Sik

Mechanisms of organ development and homeostasis and tumor development

Bryce Paschal

Paschal, Bryce M.

Nuclear Transport, Signaling, and Cancer

Shayn Peirce-Cottler

Peirce-Cottler, Shayn M.

Tissue Engineering and Regeneration, Computational Systems Biology, Vascular Growth and Remodeling, Stem Cell Therapies

Lucy Pemberton

Pemberton, Lucy F.

Nuclear Transport in Chromatin Assembly and Transcriptional Regulation

Edward Perez-Reyes

Perez-Reyes, Edward

Exploring epilepsy circuits then preventing seizures using AAV-based gene therapies.

Owen Pornillos

Pornillos, Owen

Structure and assembly of HIV, virus/host interactions, structural biology of the innate immune system

Benjamin Purow

Purow, Benjamin W.

Novel therapeutic approaches to brain cancers and to other neurologic diseases

Kodi Ravichandran

Ravichandran, Kodi S.

Apoptotic cell clearance mechanisms in health and disease

Stefanie Redemann

Redemann, Stefanie

Chromosome segregation and aneuploidy in meiosis and mitosis

David Rekosh

Rekosh, David M.

Human Immunodeficiency; Virus Gene Expression

Jeffrey Saucerman

Saucerman, Jeffrey J.

Roles of complex signaling networks involved in the regulation of cardiovascular function and disease

Nathan Sheffield

Sheffield, Nathan

computational biology & bioinformatics; high performance computing; epigenomics & chromatin; pediatric cancer; computational regulatory genomics; machine learning

Weibin Shi

Shi, Weibin

Molecular and genetic determinants of atherosclerosis and cardiometabolic disorders.

Sarah Siegrist

Siegrist, Sarah

Regulation of neural stem cell proliferation during development and adulthood

Jeffrey Smith

Smith, Jeffrey S.

Transcriptional Silencing and Aging in Yeast

P. Todd Stukenberg

Stukenberg, P. Todd

Mechanisms of chromosome segregation in Mitosis and generation of Chromosomal Instability in tumors

Lukas Tamm

Tamm, Lukas K.

Biomembrane Structure and Function; Cell Entry of Enveloped Viruses; Neurosecretion by Exocytosis; Structure of Bacterial Pathogen Membrane Proteins; Lipid-Protein Interactions

Christine Thisse

Thisse, Christine I.

Molecular Mechanisms of Early Vertebrate Development and Morphogenesis. Application to Stem Cell Biology and Regenerative Medicine

B. Venton

Venton, B. Jill

Analytical Neurochemistry; Dopamine and Serotonin Neurotransmission in Drosophila; Mechanisms of rapid adenosine signaling in rodents

Yuh-Hwa Wang

Wang, Yuh-Hwa

Genome instability in cancer and repeat expansion diseases

Michael Wiener

Wiener, Michael C.

Structure/function of integral membrane proteins; structural biophysics; enzymology and virology of ZMPSTE24; sparse-constraint structure determination; technology development

Bettina Winckler

Winckler, Bettina

Endosomal function and dysfunction in neurons. Development of the nervous system: cytoskeleton and membrane traffic in axon and dendrite growth.

David Wotton

Wotton, David

Regulation of Gene Expression, Development and Tumor Progression by TGF beta Signaling

Martin Wu

Wu, Martin

Research: microbial evolution and ecology, microbial genomics, metagenomics, bioinformatics, phylogenomics, endosymbionts

Mark Yeager

Yeager, Mark

Cardiac Gap Junction Membrane Channels / IntegrinsWater Channels / Rotavirus / Reovirus / Retrovirus

Chongzhi Zang

Zang, Chongzhi

Bioinformatics methodology development; Epigenetics and chromatin biology; Transcriptional regulation; Cancer genomics and epigenomics; Statistical methods for biomedical data integration; Theoretical and computational biophysics

J. Julius Zhu

Zhu, J. Julius

Neural Circuits in Healthy and Diseased Brains

Jochen Zimmer

Zimmer, Jochen

Transport of biopolymers across biological membranes with a particular interest in polysaccharide and protein translocation.

Hui Zong

Zong, Hui

Early detection, cancer prevention, and tumor microenvironment