The Pediatric Center of Excellence in Nephrology (PCEN) at the University of Virginia (UVA) calls for applications for Pilot and Feasibility Projects (PFPs) within the general theme of the Center “Kidney Development: cell fate and precursors of disease in the young and adult”. The overall objective of the center is to improve the management of children with kidney diseases and hypertension. Although the central theme of the center is related to the developmental basis of kidney disease in children, applications proposing fundamental technological advances to solve major mechanisms or develop novel therapeutic strategies will be welcome. The PFPs have been designed for individuals within the early phase of their careers. However, senior investigators planning to change their focus to study kidney development will also be considered.