Pediatric Center of Excellence in Nephrology

The Center of Excellence in Pediatric Nephrology strives to provide a coordinated, interdisciplinary, and inter-institutional approach to studying the development of the kidney during embryonic, fetal and postnatal life.

The center brings together investigators from the University of Virginia and Tulane University. The main research theme is “Kidney Development and Disease: Cell Fate and Precursors of Disease in the Young and Adult.”

Broadly, the proposed research deals with fundamental questions of clinical relevance in Pediatric Nephrology such as the understanding of kidney morphogenesis and homeostasis in health and disease.

The experimental approaches range from examination of epigenetic mechanisms that control cell fate, plasticity, and identity and the cellular signals underlying the phenotypic transformation that occurs during kidney injury and repair.

 

UVA Discovery a Major Step Toward Growing Kidneys

Researchers at the Pediatric Center of Excellence in Nephrology at UVA have identified the cells that give rise to the blood vessels within the kidney.

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Applications for Pilot and Feasibility Projects

The Pediatric Center of Excellence in Nephrology (PCEN) at the University of Virginia (UVA) calls for applications for Pilot and Feasibility Projects (PFPs) within the general theme of the Center “Kidney Development: cell fate and precursors of disease in the young and adult”.

Central Research

Researchers at the center are focused on two main projects: RBPJ and cell fate in the kidney vasculature and regenerative capacity of the kidney after ureteral obstruction release.
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Pilot Program

The pilot and feasibility program encourages young and established investigators to take up research relevant to kidney development and disease and speed the acquisition of knowledge that can be applied to treatment of children with renal and urological diseases.
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Enrichment Program

The center aims to inspire, attract and stimulate the interest of young individuals in Pediatric Nephrology research.
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National Institute of Diabetes and Digestive and Kidney Diseases

NIDDK conducts and supports research on many of the most common, costly, and chronic conditions to improve health.