Archive — Publications from Trainees 2014-15

Publication Author & Summary
NCBI-pubmed Arandjelovic S, Ravichandran KS. Phagocytosis of apoptotic cells in homeostasis. Nature immunology. 2015;16(9):907-17.
NCBI-pubmed Tosello-Trampont AC, Krueger P, Narayanan S, Landes SG, Leitinger N, Hahn YS. NKp46 NK cells attenuate metabolism-induced hepatic fibrosis by regulating macrophage activation. Hepatology. 2015. doi: 10.1002/hep.28389
NCBI-pubmed Buckley MW, Trampont PC, Arandjelovic S, Fond AM, Juncadella IJ, Ravichandran KS. ShcA regulates late stages of T cell development and peripheral CD4+ T cell numbers. Journal of Immunology. 2015;194(4):1665-76
NCBI-pubmed Peske JD, Thompson ED, Gemta L, Baylis RA, Fu YX, Engelhard VH. Effector lymphocyte-induced lymph node-like vasculature enables naive T-cell entry into tumours and enhanced anti-tumour immunity. Nature communications. 2015;6:7114
NCBI-pubmed Louveau A, Smirnov I, Keyes TJ, Eccles JD, Rouhani SJ, Peske JD, Derecki NC, Castle D, Mandell JW, Lee KS, Harris TH, Kipnis J. Structural and functional features of central nervous system lymphatic vessels. Nature. 2015;523(7560):337-41.
NCBI-pubmed Peske JD, Woods AB, Engelhard VH. Control of CD8 T-Cell Infiltration into Tumors by Vasculature and Microenvironment. Advances in cancer research. 2015;128:263-307
NCBI-pubmed Lobo PI, Schlegel KH, Bajwa A, Huang L, Wang B, Ye H, Tedder TF, Kinsey GR, Okusa MD. Natural IgM switches the function of LPS activated murine bone marrow dendritic cells (BMDC) to a “regulatory” DC that suppresses innate inflammation.  Journal of Immunology. 195(11):5215-26, 2015.
NCBI-pubmed Fond AM, Lee CS, Schulman IG, Kiss RS, Ravichandran KS. Apoptotic cells trigger a membrane-initiated pathway to increase ABCA1. The Journal of clinical investigation. 2015;125(7):2748-58
NCBI-pubmed Cowardin CA, Kuehne SA, Buonomo EL, Marie CS, Minton NP, Petri WA, Jr. Inflammasome activation contributes to interleukin-23 production in response to Clostridium difficile. mBio. 2015;6(1).
NCBI-pubmed Hufford MM, Kim TS, Sun J, Braciale TJ. The effector T cell response to influenza infection. Current topics in microbiology and immunology. 2015;386:423-55.
NCBI-pubmed Buonomo EL, Petri WA, Jr. The Bug Stops Here: Innate Lymphoid Cells in Clostridium difficile Infection. Cell host & microbe. 2015;18(1):5-6.
NCBI-pubmed Yao S, Jiang L, Moser EK, Jewett LB, Wright J, Du J, Braciale TJ, Sun J. Control of pathogenic effector T-cell activities in situ by PD-L1 expression on respiratory inflammatory dendritic cells during respiratory syncytial virus infection. Mucosal immunology. 2015;8(4):746-59
NCBI-pubmed Moser EK, Sun J, Kim TS, Braciale TJ. IL-21R signaling suppresses IL-17+ gamma delta T cell responses and production of IL-17 related cytokines in the lung at steady state and after Influenza A virus infection. PloS one. 2015;10(4)
NCBI-pubmed Filiano AJ, Kipnis J. Breaking bad blood: beta2-microglobulin as a pro-aging factor in blood. Nature medicine. 2015;21(8):844-5
NCBI-pubmed Rouhani SJ, Eccles JD, Riccardi P, Peske JD, Tewalt EF, Cohen JN, Liblau R, Makinen T, and Engelhard VH.  Roles of lymphatic endothelial cells expressing peripheral tissue antigens in CD4 T-cell tolerance induction.  Nature Communications.  2015;6:6771.
NCBI-pubmed Coquery CM, Loo WM, Wade NS, Bedermen AG, Tung KS, Lewis JE, Hess H, Erickson LD.  BAFF Regulates Follicular Helper T Cells and Affects Their Accumulation and Interferon-γ Production in Autoimmunity.  Arthritis Rheumatol. 2015 Mar;67(3):773-84.
NCBI-pubmed Bajwa A, Rosin DL, Chroscicki P, Lee S, Dondeti K, Ye H, Kinsey GR, Stevens BK, Jobin K, Kenwood BM, Hoehn KL, Lynch KR, and Okusa MD. 2015. Sphingosine 1-phosphate receptor-1 enhances mitochondrial function and reduces Cisplatin-induced tubule injury. Journal of the American Society of Nephrology : JASN 26:908-925.
NCBI-pubmed Krueger PD, Kim TS, Sung SS, Braciale TJ, and Hahn YS.  Liver-Resident CD103+ Dendritic Cells prime antiviral CD8+ T cells in situ.
J Immunol. 23 February 2015
NCBI-pubmed Zarling AL, Obeng RC, Desch AN,  Pinczewski J, Cummings KL, Deacon DH, Conaway M, Slingluff CL, and Engelhard VH. MHC-Restricted Phosphopeptides from Insulin Receptor Substrate-2 and CDC25b Offer Broad-BasedImmunotherapeutic Agents for Cancer.  Cancer Research. Dec. 2014
NCBI-pubmed Penberthy KK, Juncadella IJ, Ravichandran KS.  Apoptosis and engulfment by bronchial epithelial cells. Implications for allergic airway inflammation. Annals of the American Thoracic Society. 2014;11 Suppl 5:S259-62.
NCBI-pubmed Gigliotti J, Okusa MD, The spleen: The forgotten organ in acute kidney injury of critical illness.Nephron Clin. Pract. 127(1-4):153-157, 2014.
NCBI-pubmed Vincent IS, Okusa MD. Biology of Renal Recovery: Molecules, Mechanisms, and Pathways. Nephron Clin Pract. 127(1-4):10-14, 2014.
NCBI-pubmed Wei H, Nash WT, Makrigiannis AP, Brown MG. Impaired NK-cell education diminishes resistance to murine CMV infection. European journal of immunology. 2014;44(11):3273-82
NCBI-pubmed Filiano AJ, Gadani SP, Kipnis J. Interactions of innate and adaptive immunity in brain development and function. Brain research. 2014.
NCBI-pubmed Moser EK, Hufford MM, Braciale TJ. Late Engagement of CD86 after Influenza Virus Clearance Promotes Recovery in a FoxP3+ Regulatory T Cell Dependent Manner. PLoS pathogens. 2014;10(8)
NCBI-pubmed Dolina JS, Braciale TJ, Hahn YS. Liver-primed CD8+ T cells suppress antiviral adaptive immunity through galectin-9-independent T-cell immunoglobulin and mucin 3 engagement of high-mobility group box 1 in mice. Hepatology.
NCBI-pubmed Lee HC, Narayanan S, Park SJ, Seong SY, Hahn YS. Transcriptional regulation of IFN-lambda genes in hepatitis C virus-infected hepatocytes via IRF-3.IRF-7.NF-kappaB complex. The Journal of Biological Chemistry. 2014;289(8):5310-9.
NCBI-pubmed Radjavi A, Smirnov I, Kipnis J. Brain antigen-reactive CD4+ T cells are sufficient to support learning behavior in mice with limited T cell repertoire. Brain Behav Immun. 2014 Jan;35:58-63.
NCBI-pubmed Cohen JN, Tewalt EF, Rouhani SJ, Buonomo EL, Bruce AN, Xu X, Bekiranov S, Fu YX, Engelhard VH. Tolerogenic properties of lymphatic endothelial cells are controlled by the lymph node microenvironment. PLoS One. 2014;9(2).
NCBI-pubmed Madan R, Guo X, Naylor C, Buonomo EL, Mackay D, Noor Z, Concannon P, Scully KW, Pramoonjago P, Kolling GL, Warren CA, Duggal P, Petri WA Jr. Role of leptin-mediated colonic inflammation in defense against Clostridium difficile colitis. Infect Immun. 2014 Jan;82(1):341-9.
NCBI-pubmed Das S, Sarkar A, Ryan KA, Fox S, Berger AH, Juncadella IJ, Bimczok D, Smythies LE, Harris PR,Ravichandran KS, Crowe SE, Smith PD, Ernst PB. Brain angiogenesis inhibitor 1 is expressed by gastric phagocytes during infection with Helicobacter pylori and mediates the recognition and engulfment of human apoptotic gastric epithelial cells. FASEB J. 2014 Feb 7.
NCBI-pubmed Kennedy JL, Shaker M, McMeen V, Gern J, Carper H, Murphy D, Lee WM, Bochkov YA, Vrtis RF,Platts-Mills T, Patrie J, Borish L, Steinke JW, Woods WA, Heymann PW. Comparison of Viral Load in Individuals with and without Asthma during Infections with Rhinovirus. Am J Respir Crit Care Med. 2014 Mar 1;189(5):532-9.
NCBI-pubmed Kim TS, Gorski SA, Hahn S, Murphy KM, Braciale TJ. Distinct Dendritic Cell Subsets Dictate the Fate Decision between Effector and Memory CD8(+) T Cell Differentiation by a CD24-Dependent Mechanism. Immunity. 2014 Mar 20;40(3):400-13.
NCBI-pubmed Poon IK, Chiu YH, Armstrong AJ, Kinchen JM, Juncadella IJ, Bayliss DA, Ravichandran KS. Unexpected link between an antibiotic, pannexin channels and apoptosis. Nature. 2014 Mar 20;507(7492):329-34.