Archive — Publications from Trainees 2017

Publications

Pathogenic CD4+ T cells in patients with asthma.

Muehling LM, L awrence MG, Woodfolk JA. J Allergy Clin Immunol. 2017 Dec;140(6):1523-1540. doi: 10.1016/j.jaci.2017.02.025. Epub 2017 Apr 22. Review.PMID: 28442213

Neuroimmune Interactions in Inflammation and Acute Kidney Injury.

Inoue T, Tanaka S, Okusa MD. Front Immunol. 2017 Aug 9;8:945. doi: 10.3389/fimmu.2017.00945. eCollection 2017. Review.PMID: 28848551

Natural IgM and TLR Agonists Switch Murine Splenic Pan-B to “Regulatory” Cells That Suppress Ischemia-Induced Innate Inflammation <i>via</i> Regulating NKT-1 Cells.

Lobo PI, Schle gel KH, Bajwa A, Huang L, Okusa MD. Front Immunol. 2017 Aug 23;8:974. doi: 10.3389/fimmu.2017.00974. eCollection 2017.PMID: 28878768

Myeloid Cells in the Central Nervous System.

Herz J, Filian o AJ, Smith A, Yogev N, Kipnis J. Immunity. 2017 Jun 20;46(6):943- 956. doi: 10.1016/j.immuni.2017.06.007. Review.PMID: 28636961

Mitochondrial dysregulation and glycolytic insufficiency functionally impair CD8 T cells infiltrating human renal cell carcinoma.

Siska PJ, Bec kermann KE, Mason FM, Andrejeva G, Greenplate AR, Sendor AB, Chiang YJ, Corona AL, Gemta LF, Vincent BG, Wang RC, Kim B, Hong J, Chen CL, Bullock TN, Irish JM, Rathmell WK, Rathmell JC. JCI Insight. 2017 Jun 15;2(12). pii: 93411. doi: 10.1172/jci.insight.93411. [Epub ahead of print]PMID: 28614802

Nonpharmacological, Biomechanical Approaches to Control Inflammation in Acute Kidney Injury.

Tanaka S, Inoue T, Hossack JA, Okusa MD. Nephron. 2017;137(4):277-281. doi: 10.1159/000477218. Epub 2017 Jun 9. PMID: 2859519

The heterogeneity of tumor-infiltrating CD8+ T cells in metastatic melanoma distorts their quantification: how to manage heterogeneity?

Obeid JM, Hu Y, Erdag G, Leick KM, Slingluff CL Jr. Melanoma Res. 2017 Jun;27(3):211-217. doi: 10.1097/CMR.0000000000000330. PMID: 28118270

IL233, A Novel IL-2 and IL-33 Hybrid Cytokine, Ameliorates Renal Injury.

Stremska ME, Jose S, Sabapathy V, Huang L, Bajwa A, Kinsey GR, Sharma PR, Mohammad S, Rosin DL, Okusa MD, Sharma R. J Am Soc Nephrol. 2017 Sep;28(9):2681-2693. doi: 10.1681/ASN.2016121272. Epub 2017 May 24. PMID: 2853938

Lineage-Specific Metabolic Properties and Vulnerabilities of T Cells in the Demyelinating Central Nervous System

Seki SM, Stevenson M, Rosen AM, Arandjelovic S, Gemta L, Bullock TNJ, Gaultier A. J Immunol. 2017 Jun 15;198(12):4607-4617. doi: 10.4049/jimmunol.1600825. Epub 2017 May 15. PMID: 28507026

Peptide-binding motifs of two common equine class I MHC molecules in Thoroughbred horses.

Bergmann T, Lindvall M, Moore E, Moore E, Sidney J, Miller D, Tallmadge RL, Myers PT, Mal aker SA, Shabanowitz J, Osterrieder N, Peters B, Hunt DF, Antczak DF, Sette A. Immunogenetics. 2017 May;69(5):351-358. doi: 10.1007/s00251-017-0978-6. Epub 2017 Mar 18. PMID: 28315936

Regulation of Transcription Factors by Reactive Oxygen Species and Nitric Oxide in Vascular Physiology and Pathology

Kohlgrüber S, Upadhye A, Dyballa-Rukes N, McNamara CA, Altschmied J. Antioxid Redox Signal. 2017 May 1;26(13):679-699. doi: 10.1089/ars.2016.6946. Epub 2017 Jan 4. Review. PMID: 27841660

Identification of Glycopeptides as Posttranslationally Modified Neoantigens in Leukemia

Malaker SA, Penny SA, Steadman LG, Myers PT, Loke JC, Raghavan M, Bai DL, Shabanowitz J, Hunt DF, Cobbold M. Cancer Immunol Res. 2017 May;5(5):376-384. doi: 10.1158/2326-6066.CIR-16-0280. Epub 2017 Mar 17.PMID: 28314751

The Arabidopsis O-fucosyltransferase SPINDLY activates nuclear growth repressor DELLA

Zentella R, Sui N, Barnhill B, Hsieh WP, Hu J, Shabanowitz J, Boyce M, Olszewski NE, Zhou P, Hunt DF, Sun TP. Nat Chem Biol. 2017 May;13(5):479-485. doi: 10.1038/nchembio.2320. Epub 2017 Feb 28.PMID: 28244988

Sphingosine Kinase 2 Deficiency Attenuates Kidney Fibrosis <i>via</i> IFN-g

Bajwa A, Huan g L, Kurmaeva E, Ye H, Dondeti KR, Chroscicki P, Foley LS, Balogun ZA, Alexander KJ, Park H, Lynch KR, Rosin DL, Okusa MD.J Am Soc Nephrol. 2017 Apr;28(4):1145-1161. doi:10.1681/ASN.2016030306. Epub 2016 Oct 31. PMID: 27799486

The antigenic identity of human class I MHC phosphopeptides is critically dependent upon phosphorylation status

Mohammed F, Stones DH, Zarling AL, Willcox CR, Shabanowitz J, Cummings KL, Hunt DF, Cobbold M, Engelhard VH, Willcox BE. Oncotarget. 2017 Apr 8;8(33):54160-54172. doi:10.18632/oncotarget.16952. eCollection 2017 Aug 15. PMID: 28903331

Microbiome-mediated neutrophil recruitment via CXCR2 and protection from amebic colitis

Watanabe K, Gilchrist CA, Uddin MJ, Burgess SL, Abhyankar MM, Moonah SN, Noor Z, Donowitz JR, Schneider BN, Arju T, Ahmed E, Kabir M, Alam M, Haque R, Pramoonjago P, Mehrad B, Petri WA Jr.
PLoS Pathog. 2017 Aug 17;13(8):e1006513. doi: 10.1371/journal.ppat.1006513. eCollection 2017 Aug.PMID: 28817707

Parasitic Protozoa and Interactions with the Host Intestinal Microbiota

Burgess SL, Gilchrist CA, Lynn TC, Petri WA Jr.
Infect Immun. 2017 Jul 19;85(8). pii: e00101-17. doi: 10.1128/IAI.00101-17. Print 2017 Aug. Review. PMID: 28584161

Nonspecific Effects of Oral Polio Vaccine on Diarrheal Burden and Etiology Among Bangladeshi Infants

Upfill-Brown A, Taniuchi M, Platts-Mills JA, Kirkpatrick B, Burgess SL, Oberste MS, Weldon W, Houpt E, Haque R, Zaman K, Petri WA Jr.
Clin Infect Dis. 2017 Aug 1;65(3):414-419. doi: 10.1093/cid/cix354. PMID: 28444240

How and why do T cells and their derived cytokines affect the injured and healthy brain?

Filiano AJ, Gadani SP, Kipnis J.
Nat Rev Neurosci. 2017 Jun;18(6):375-384. doi: 10.1038/nrn.2017.39. Epub 2017 Apr 27. Review.
PMID: 2844678

High-Throughput Particle Uptake Analysis by Imaging Flow Cytometry

Smirnov A, Solga MD, Lannigan J, Criss AK.
Curr Protoc Cytom. 2017 Apr 3;80:11.22.1-11.22.17. doi: 10.1002/cpcy.19.PMID: 28369762

Effect of probiotic on innate inflammatory response and viral shedding in experimental rhinovirus infection – a randomised controlled trial

Turner RB, Woodfolk JA, Borish L, Steinke JW, Patrie JT, Muehling LM, Lahtinen S, Lehtinen MJ.
Benef Microbes. 2017 Apr 26;8(2):207-215. doi: 10.3920/BM2016.0160. Epub 2017 Mar 27.PMID: 2834340

Immunoregulatory Role of NK Cells in Tissue Inflammation and Regeneration

Tosello-Trampont A, Surette FA, Ewald SE, Hahn YS.
Front Immunol. 2017 Mar 20;8:301. doi: 10.3389/fimmu.2017.00301. eCollection 2017. Review.PMID: 28373874

Murine Cytomegalovirus Disrupts Splenic Dendritic Cell Subsets via Type I Interferon-Dependent and -Independent Mechanisms

Nash WT, Gillespie AL, Brown MG.
Front Immunol. 2017 Mar 9;8:251. doi: 10.3389/fimmu.2017.00251. eCollection 2017.PMID: 28337202

Two lytic transglycosylases in Neisseria gonorrhoeae impart resistance to killing by lysozyme and human neutrophils

Ragland SA, Schaub RE, Hackett KT, Dillard JP, Criss AK.
Cell Microbiol. 2017 Mar;19(3). doi: 10.1111/cmi.12662. Epub 2016 Nov 3.PMID: 27597434

Vitamin D in hematological disorders and malignancies

Kulling PM, Olson KC, Olson TL, Feith DJ, Loughran TP Jr.
Eur J Haematol. 2017 Mar;98(3):187-197. doi: 10.1111/ejh.12818. Epub 2016 Nov 21. Review.PMID: 27743385

Role of Eosinophils and Tumor Necrosis Factor Alpha in Interleukin-25-Mediated Protection from Amebic Colitis

Noor Z, Watanabe K, Abhyankar MM, Burgess SL, Buonomo EL, Cowardin CA, Petri WA Jr.
MBio. 2017 Feb 28;8(1). pii: e02329-16. doi: 10.1128/mBio.02329-16. PMID: 28246365

Spatially resolved microfluidic stimulation of lymphoid tissue ex vivo

Ross AE, Belanger MC, Woodroof JF, Pompano RR.
Analyst. 2017 Feb 14;142(4):649-659. doi: 10.1039/c6an02042a. Epub 2016 Nov 30.PMID: 27900374

Characterization of meningeal type 2 innate lymphocytes and their response to CNS injury

Gadani SP, Smirnov I, Smith AT, Overall CC, Kipnis J.
J Exp Med. 201 7 Feb;214(2):285-296. doi: 10.1084/jem.20161982. Epub 2016 Dec 19.PMID: 27994070

Influenza A induces dysfunctional immunity and death in MeCP2-overexpressing mice

Cronk JC, Herz J, Kim TS, Louveau A, Moser EK, Sharma AK, Smirnov I, Tung KS, Braciale TJ, Kipnis J. JCI Insight. 2017 Jan 26;2(2):e88257. doi: 10.1172/jci.insight.88257.PMID: 28138553

Alveolar Macrophages Prevent Lethal Influenza Pneumonia By Inhibiting Infection Of Type-1 Alveolar Epithelial Cells

Cardani A, Boulton A, Kim TS, Braciale TJ.
PLoS Pathog. 2017 Jan 13;13(1):e1006140. doi: 10.1371/journal.ppat.1006140. eCollection 2017 Jan.PMID: 28085958

Editorial: Masters of fate: the APC cytokine milieu as a key regulator of distinct Tfh cell subsets

Cox KM, Erickson LD. J Leukoc Biol. 2017 Jan;101(1):1-3. doi: 10.1189/jlb.1CE0816-351R. No abstract available.PMID: 28049141

Expression of scavenger receptor-AI promotes alternative activation of murine macrophages to limit hepatic inflammation and fibrosis

Labonte AC, Sung SJ, Jennelle LT, Dandekar AP, Hahn YS.
Hepatology. 2017 Jan;65(1):32-43. doi: 10.1002/hep.28873. Epub 2016 Nov 22. PMID: 27770558

Heterogeneity of CD8<sup>+</sup> tumor-infiltrating lymphocytes in non-small-cell lung cancer: impact on patient prognostic assessments and comparison of quantification by different sampling strategies

Obeid JM, Wages NA, Hu Y, Deacon DH, Slingluff CL Jr.
Cancer Immunol Immunother. 2017 Jan;66(1):33-43. doi: 10.1007/s00262-016-1908-4. Epub 2016 Oct 21. PMID: 27770170

Murine liver-resident group 1 innate lymphoid cells regulate optimal priming of anti-viral CD8+ T cells

Krueger PD, Narayanan S, Surette FA, Brown MG, Sung SJ, Hahn YS.
J Leukoc Biol. 2017 Jan;101(1):329-338. doi: 10.1189/jlb.3A0516-225R. Epub 2016 Aug 4. PMID: 27493244