Publications from Trainees


Formation and phenotypic characterization of CD49a, CD49b and CD103 expressing CD8 T cell populations in human metastatic melanoma.

Melssen MM, Olson W, Wages NA, Capaldo BJ, Mauldin IS, Mahmutovic A, Hutchison C, Melief CJM, Bullock TN, Engelhard VH, Slingluff CL Jr.
Oncoimmunology. 2018 Aug 6;7(10):e1490855. eCollection 2018. PMID:30288359

Morphological and Functional Analysis of CNS-Associated Lymphatics.

Herz J, Louveau A, Da Mesquita S, Kipnis J.
Methods Mol Biol. 2018;1846:141-151. PMID:30242757

Identification and Characterization of Tertiary Lymphoid Structures in Murine Melanoma.

Rodriguez AB, Peske JD, Engelhard VH.
Methods Mol Biol. 2018;1845:241-257. PMID:30141017

Meningeal whole mount preparation and characterization of neural cells by flow cytometry.

Louveau A, Filiano AJ, Kipnis J.
Curr Protoc Immunol. 2018 Apr;121(1).PMID: 30008983

Focal adhesion kinase (FAK) deficiency in mononuclear phagocytes alters murine breast tumor progression.

Llewellyn RA, Gutknecht MF, Thomas KS, Conaway MR, Bouton AH.
Am J Cancer Res. 2018 Apr 1;8(4):675-687. eCollection 2018. PMID: 29736312

Peripherally derived macrophages can engraft the brain independent of irradiation and maintain an identity distinct from microglia.

Cronk JC, Filiano AJ, Louveau A, Marin I, Marsh R, Ji E, Goldman DH, Smirnov I, Geraci N, Acton S, Overall CC, Kipnis J.
J Exp Med. 2018 Jun 4;215(6):1627-1647. PMID:29643186

c-Myb Coordinates Survival and the Expression of Genes That Are Critical for the Pre-BCR Checkpoint

Fahl SP, Daamen AR, Crittenden RB, Bender TP.
J Immunol. 2018 Apr 13. pii: ji1302303. doi: 10.4049/jimmunol.1302303. PMID: 29654210

Cancer vaccine formulation dictates synergy with CTLA-4 and PD-L1 checkpoint blockade therapy

Hailemichael Y, Woods A, Fu T, He Q, Nielsen MC, Hasan F, Roszik J, Xiao Z, Vianden C, Khong H, Singh M, Sharma M, Faak F, Moore D, Dai Z, Anthony SM, Schluns KS, Sharma P, Engelhard VH, Overwijk WW.
J Clin Invest. 2018 Apr 2;128(4):1338-1354. doi: 10.1172/JCI93303. Epub 2018 Feb 26.PMID: 29480817

Rethinking Phagocytes: Clues from the Retina and Testes

Penberthy KK, Lysiak JJ, Ravichandran KS.
Trends Cell Biol. 2018 Apr;28(4):317-327. doi: 10.1016/j.tcb.2018.01.004. Epub 2018 Feb 14. Review.PMID: 29454661

CD47 Blockade as an Adjuvant Immunotherapy for Resectable Pancreatic Cancer

Michaels AD, Newhook TE, Adair SJ, Morioka S, Goudreau BJ, Nagdas S, Mullen MG, Persily JB, Bullock TNJ, Slingluff CL Jr, Ravichandran KS, Parsons JT, Bauer TW.
Clin Cancer Res. 2018 Mar 15;24(6):1415-1425. doi: 10.1158/1078-0432.CCR-17-2283. Epub 2017 Dec 29. PMID: 29288236

Neuroimmunology in 2017: The central nervous system: privileged by immune connections

Kipnis J, Filiano AJ.
Nat Rev Immunol. 2018 Feb;18(2):83-84. doi: 10.1038/nri.2017.152. Epub 2017 Dec 27. No abstract available.PMID: 29279610

Pannexin 1 Channels as an Unexpected New Target of the Anti-Hypertensive Drug Spironolactone

Good ME, Chiu YH, Poon IKH, Medina CB, Butcher JT, Mendu SK, DeLalio LJ, Lohman AW, Leitinger N, Barrett E, Lorenz UM, Desai BN, Jaffe IZ, Bayliss DA, Isakson BE, Ravichandran KS.
Circ Res. 2018 Feb 16;122(4):606-615. doi: 10.1161/CIRCRESAHA.117.312380. Epub 2017 Dec 13. PMID: 29237722

Immunotherapy for hepatocellular carcinoma patients: is it ready for prime time?

Obeid JM, Kunk PR, Zaydfudim VM, Bullock TN, Slingluff CL Jr., Rahma OE.
Cancer Immunol Immunother. 2018 Feb;67(2):161-174. doi: 10.1007/s00262-017-2082-z. Epub 2017 Oct 20. Review. PMID: 29052780

Evaluation of SAS1B as a target for antibody-drug conjugate therapy in the treatment of pancreatic cancer

Knapp KA, Pies ES, Adair SJ, Mandal A, Mills AM, Olson WC, Slingluff CL Jr, Parsons JT, Bauer TW, Bullock TN, Herr JC. Oncotarget. 2018 Jan 4;9(10):8972-8984. doi: 10.18632/oncotarget.23944. eCollection 2018 Feb 6. PMID: 29507667

Sex, Gut, and Microglia

Louveau A, Kipnis J.
Dev Cell. 2018 Jan 22;44(2):137-138. doi: 10.1016/j.devcel.2018.01.003.PMID: 29401417

Chanzyme TRPM7 Mediates the Ca<sup>2+</sup> Influx Essential for Lipopolysaccharide-Induced Toll-Like Receptor 4 Endocytosis and Macrophage Activation

Schappe MS, Szteyn K, Stremska ME, Mendu SK, Downs TK, Seegren PV, Mahoney MA, Dixit S, Krupa JK, Stipes EJ, Rogers JS, Adamson SE, Leitinger N, Desai BN.
Immunity. 2018 Jan 16;48(1):59-74.e5. doi: 10.1016/j.immuni.2017.11.026.PMID: 29343440

Immune Cell Infiltration and Tertiary Lymphoid Structures as Determinants of Antitumor Immunity

Engelhard VH, Rodriguez AB, Mauldin IS, Woods AN, Peske JD, Slingluff CL Jr..
J Immunol. 2018 Jan 15;200(2):432-442. doi: 10.4049/jimmunol.1701269. Review. PMID: 29311385

Single-Cell Tracking Reveals a Role for Pre-Existing CCR5+ Memory Th1 Cells in the Control of Rhinovirus-A39 After Experimental Challenge in Humans

Muehling LM, Turner RB, Brown KB, Wright PW, Patrie JT, Lahtinen SJ, Lehtinen MJ, Kwok WW, Woodfolk JA.   J Infect Dis. 2018 Jan 17;217(3):381-392. doi: 10.1093/infdis/jix514.PMID: 29309618

Pathogenesis of Neisseria gonorrhoeae in the female reproductive tract: neutrophilic host response, sustained infection, and clinical sequelae

Stevens JS, Criss AK.
Curr Opin Hematol. 2018 Jan;25(1):13-21. doi: 10.1097/MOH.0000000000000394.PMID: 29016383

Hepatocyte-derived exosomes promote T follicular regulatory cell expansion during hepatitis C virus infection

Cobb DA, Kim OK, Golden-Mason L, Rosen HR, Hahn YS.
Hepatology. 2018 Jan;67(1):71-85. doi: 10.1002/hep.29409. Epub 2017 Nov 15. PMID: 28749570

Dynamin-Related Protein 1 Deficiency Promotes Recovery from AKI.

Perry HM, Huang L, Wilson RJ, Bajwa A, Sesaki H, Yan Z, Rosin DL, Kashatus DF, Okusa MD. J Am Soc Nephrol. 2018 Jan;29(1):194-206. doi: 10.1681/ASN.2017060659. PMID: 29084809

Pathogenic CD4+ T cells in patients with asthma.

Muehling LM, L awrence MG, Woodfolk JA. J Allergy Clin Immunol. 2017 Dec;140(6):1523-1540. doi: 10.1016/j.jaci.2017.02.025. Epub 2017 Apr 22. Review.PMID: 28442213

Editorial: On matters of maturity, self-control, and responsiveness: inhibitory NK receptors in the driver’s seat?

Brown MG, Gamache A.J Leukoc Biol. 2017 Dec;102(6):1281-1284. doi: 10.1189/jlb.1CE0717-280RR. No abstract available. PMID:29191865

Context-dependent compensation among phosphatidylserine-recognition receptors.

Penberthy KK, Rival C, Shankman LS, Raymond MH, Zhang J, Perry JSA, Lee CS, Han CZ, Onengut-Gumuscu S, Palczewski K, Lysiak JJ, Ravichandran KS. Sci Rep. 2017 Nov 7;7(1):14623. doi: 10.1038/s41598-017-15191-1. PMID:29116131

Differential Expression of Homing Receptor Ligands on Tumor-Associated Vasculature that Control CD8 Effector T-cell Entry.

Woods AN, Wilson AL, Srivinisan N, Zeng J, Dutta AB, Peske JD, Tewalt EF, Gregg RK, Ferguson AR, Engelhard VH. Cancer Immunol Res. 2017 Dec;5(12):1062-1073. doi: 10.1158/2326-6066.CIR-17-0190. PMID: 29097419

Immunotherapy for hepatocellular carcinoma patients: is it ready for prime time?

Obeid JM, Kunk PR, Zaydfudim VM, Bullock TN, Slingluff CL Jr, Rahma OE. Cancer Immunol Immunother. 2018 Feb;67(2):161-174. doi: 10.1007/s00262-017-2082-z.. Review. PMID: 29052780

Using Serum IgE Antibodies to Predict Esophageal Eosinophilia in Children.

Erwin EA, Rhoda DA, Redmond M, Ly JB, Russo JM, Hill ID, Platts-Mills TAE. J Pediatr Gastroenterol Nutr. 2017 Nov;65(5):520-525. PMID: 28981449

The nonreceptor protein tyrosine kinase Pyk2 promotes the turnover of monocytes at steady state.

Llewellyn RA, Thomas KS, Gutknecht MF, Bouton AH. J Leukoc Biol. 2017 Oct;102(4):1069-1080. doi: 10.1189/jlb.1A0217-063R. Epub 2017 Jul 28. PMID: 28754799