PATH 8300: Tumors and the Immune System

PATH 8300 focuses on the dynamic interaction between the immune system and cancer. The course teaches how the immune response can contribute to the initiation and progression of cancer, yet paradoxically also play a fundamental role in constraining tumor outgrowth. The course explores the contributions of various immune cellular subsets to cancer progression and control, and delineate mechanisms by which immune effector cells recognize and control tumors, and the escape mechanisms used by tumors to ultimately evade immune-mediated control. The class involves presentation and analysis of classic and contemporary literature and the development of class-wide activities to promote deeper yet integrated understanding of the processes being studied. Students should have a strong knowledge of innate and adaptive immunity. This course meets twice a week for 1.5 hours for half a semester.