Prakash, Anupam (Luckey)
RBC alloimmunization occurs when patients make antibodies to non-ABO groups expressed on the RBC surface. There are over 100,000 potential cases of RBC alloimmunzation every year. The exact mechanisms controlling this condition is mostly unknown. My project involves with studying the role of Th2 cytokines and the transcription factor STAT6 in regulating RBC alloimmunization and germinal center development.