Rivet-Noor, Courtney (Gaultier)
Courtney Rivet-Noor is a PhD candidate in the Gaultier Lab within the Brain, Immunology, and Glia Center in the Department of Neuroscience. She is working to understand the impact that stress has on the microbiome. Stress is known to cause significant changes to the microbiome, which can in turn influence the onset of several conditions, including autoimmune disease and mental health disorders. However, the specific ways in which stress mediates changes to the host and thereby the microbiome are currently unknown. Using both in vivo mouse and in vitro organoid models, Courtney is investigating how stress changes the expression of mucins in the small intestine. Mucins are the large glycoproteins that make up the mucus that lines almost every organ and epithelium in the body. Additionally, mucins provide an attachment point and food for the microbial species that inhabit our small intestine. A better understanding of how stress influences mucins will allow us to develop targeted therapeutic strategies that could prevent the onset of harmful human pathologies.