The Beirne B. Carter Annual Lecture
The Beirne B. Carter Lecture in Immunology was established to bring a distinguished medical scientist each year to the UVA Health System. In keeping with Mr. Carter’s vision, the scientist is chosen based on his or her research accomplishments contributing to the areas of basic and clinical immunology and to our understanding of human disease and its cure.
For 2020, We are pleased to welcome Dr. David Raulet as the 24th Beirne B. Carter Lecturer. Dr. Raulet is Professor of Molecular and Cell Biology, Division of Immunology and Pathogenesis at the University of California-Berkley, the Esther and Wendy Schekman Chair in Basic Cancer Biology and Director of the Immunotherapeutics and Vaccine Research Initiative at Berkley. Dr. Raulet graduated with a Bachelor of Arts Degree in Microbiology from the University of Michigan and his Ph.D. in Biology from the Massachusetts Institute of Technology, where he studied with Michael Bevan. He received post-doctoral training at the University of Pennsylvania with Jonathan Sprent. Dr. Raulet has received multiple honors and awards for his research and has been elected to the National Academy of Sciences.
Dr. Raulet’s laboratory investigates mechanisms by which cancer cells and infected cells are recognized by natural killer cells and T cells. Further interests include mechanisms by which tumors and infectious agents naturally activate or inhibit productive responses by cytotoxic cells, or desensitize the cells by inducing anergy with the goal to harness these findings to improve existing immunotherapies for cancer and design new ones. The Raulet Lab has employed their understanding of NK recognition, activation, and inhibition to establish therapy combinations that super-activate NK cells, while at the same time preventing desensitization and inhibition of the cells. These approaches have promise for activating T cell responses as well.
Scroll down to see view the lectures over the years.
No Beirne B. Carter Lecture for 2019
No Beirne B. Carter Lecture for 2017
Ralph Steinman, MD, PhD
Department of Cell Physiology and Immunology, Rockefeller University
The control of immunity and tolerance by dendritic cells
Gerald R. Crabtree, MD
Professor of Pathology and Developmental Biology, Stanford University School of Medicine
Converting graded signals to discrete developmental outcomes
Philippa Marrack, PhD
Investigator, Department of Immunology, Howard Hughes Medical Institute, National Jewish Medical and Research Center
T cell life, death and memory
Paul M. Allen, PhD
Robert L. Kroc Professor of Pathology & Immunology, Department of Pathology & Immunology, Washington University
Physiology of Tumor Rejection: Insights from a Transgenic Model
Craig Thompson, MD
Director, Madlyn Abramson Family Cancer Research Institute, University of Pennsylvania Cancer Center
Control of lymphocyte survival: implications for lymphocytes in health and disease
Roger M. Perlmutter, MD, PhD
Senior Vice President of Research, Merck & Co., Inc.
The LNK Family of Signal Transducing Molecules
Peter C. Doherty, PhD
St Jude’s Children Research Hospital
Immunity to a Persistent Gamma Herpesvirus
Klaus Rajewsky, MD
Institute for Genetics, University of Cologne
Genetic Approaches to the Study of Normal and Malignant B Cell Development
Richard Klauser, MD
Chief, Cell Biology abd Metabolism Branch, National Institutes of Child Health and Development
A Cell Biologist Looks at the T Cell Receptor
Leroy Hood, MD, PhD
University of Washington School of Medicine
T Cell Receptors: Molecular Recognition and Autoimmunity
Hugh O. McDevitt, MD
Stanford University School of Medicine
Peptide Interactions with Class II MHC Molecules in Experimental Allergic Encephalomyelitis