News Archives

4/1/22 Dietary fibre, the gut microbiota and blood pressure

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3/25/22 Immunity and Immunopathogy after acute COVID-19

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3/18/22 Regulation of Endothelial Cell Specialization

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2/25/22 Planning and Responding to Pandemics in the 21st Century: The Role of Data and Computing

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2021 Circulation Research Best Manuscript Awards

Congratulations to Dr. Maria Luisa Sequeira-Lopez and colleagues for receiving a 2021 Circulation Research Best Manuscript Award for your article “Renin Cell Baroreceptor, a Nuclear Mechanotransducer Central for Homeostasis” published in May 2021.

1/14/22 Deconstruct an intricate multi-cell network in medulloblastoma with a cutting-edge mouse model

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Renin Cell Baroreceptor, a Nuclear Mechanotransducer Central for Homeostasis

CHRC scientist, Dr. Maria Luisa Sequeira-Lopez and team publish article. Citation: Watanabe, H., Belyea, B. C., Paxton, R. L., Li, M., Dzamba, B. J., DeSimone, D. W., Gomez, R. A., & Sequeira-Lopez, M. L. (2021). Renin cell baroreceptor, a nuclear mechanotransducer central for homeostasis. Circulation Research, 129(2), 262–276. https://doi.org/10.1161/circresaha.120.318711

Estimating Nephron Number from Biopsies: Impact on Clinical Studies

CHRC pediatric nephrologist, Jennifer Charlton, MD and colleagues publish article. Citation: Darya Morozov, Neda Parvin, Mark Conaway, Gavin Oxley, Edwin Baldelomar, Aleksandra Cwiek, Kimberly deRonde, Scott Beeman, Jennifer Charlton and Kevin Bennett JASN November 2021, ASN.2021070998; DOI: https://doi.org/10.1681/ASN.2021070998

11/12/21 The Role of Nutrition During the First 1,000 Days of Life in Child Development and Human Capital in Low- and Middle-Income Countries”

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Effect of scheduled antimicrobial and nicotinamide treatment on linear growth in children in rural Tanzania: A factorial randomized, double-blind, placebo-controlled trial

CHRC researcher Marc D. DeBoer, MD and colleagues publish article. Citation: DeBoer, M. D., Platts-Mills, J. A., Elwood, S. E., Scharf, R. J., McDermid, J. M., Wanjuhi, A. W., Jatosh, S., Katengu, S., Parpia, T. C., Rogawski McQuade, E. T., Gratz, J., Svensen, E., Swann, J. R., Donowitz, J. R., Mdoe, P., Kivuyo, S., Houpt, E. R., & Mduma, E. (2021). Effect of scheduled antimicrobial and nicoti …

10/22/21 Monitoring of regional oxygen saturation by near infrared spectroscopy and outcomes in neonates following cardiac surgery

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Killed whole-genome reduced-bacteria surface-expressed coronavirus fusion peptide vaccines protect against disease in a porcine model

CHRC researcher Steven L. Zeichner, MD, PhD and colleagues publish article. Citation: Maeda, D. L., Tian, D., Yu, H., Dar, N., Rajasekaran, V., Meng, S., Mahsoub, H., Sooryanarain, H., Wang, B., Heffron, C. L., Hassebroek, A., LeRoith, T., Meng, X.-J., & Zeichner, S. L. (2021). Killed whole genome-reduced bacteria surface-expressed coronavirus fusion peptide vaccines protect against disease in …

Minicells from Highly Genome Reduced Escherichia coli: Cytoplasmic and Surface Expression of Recombinant Proteins and Incorporation in the Minicells

CHRC researcher Steven L. Zeichner, MD, PhD and colleagues publish article. Citation: Yu, H., Khokhlatchev, A. V., Chew, C., Illendula, A., Conaway, M., Dryden, K., Maeda, D. L., Rajasekaran, V., Kester, M., & Zeichner, S. L. (2021). Minicells from Highly GENOME REDUCED Escherichia COLI: CYTOPLASMIC and SURFACE expression of recombinant proteins and incorporation in THE MINICELLS. https://doi. …

9/24/21 Steps for predictive monitoring in the NICU: Physiology, Data, Math, and Implementation

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9/10/21 Exercise-induced mitochondrial remodeling: Cash for Clunkers

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One Vaccine to Rule Them All

UVA Health’s Dr. Steven L. Zeichner and his colleague at Virginia Tech, Dr. Xiang-Jin Meng are developing a vaccine that could help contain both current and future variants of the COVID-19 virus – including the Delta variant currently plaguing the United States, and other variants that might crop up in the coming months and years.

AFTER 60 YEARS, SCIENTISTS FIND THE MISSING LINK IN OUR BODY’S BLOOD PRESSURE CONTROL

7/16/21 Understanding and treating HUS: Use of engineered kidney microvessels to investigate Shiga toxin mediated endothelial injury & therapeutic approaches

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Agnieszka Swiatecka-Urban, MD, Professor of Pediatrics, Chief of UVA Pediatric Nephrology

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Jamie Zoellner, PhD, RD, Professor, Department of Public Health Science

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Chongzhi Zang, PhD, Assistant Professor, Public Health Sciences Center for Public Health Genomics

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New Vaccine by UVA, Tech May Offer Broad Protection From Coronaviruses

UVA and Virginia Tech team up to test COVID-19 vaccine in pigs

Scientists at UVa, Virginia Tech develop possible COVID-19 vaccine

Christine I. Thisse, PhD Professor, Department of Cell Biology

Child Health Research Center   Christine I. Thisse, PhD Professor, Department of Cell Biology “Building a Mammalian Embryo in vitro from Pluripotent Stem Cells ”  ZOOM MEETING Friday, April 2, 2021  Time 12:00pm – 1:00pm Key messages/learning objectives: Understand limitations of the current approaches used in the stem cell field for building tissues and organs in vitro. Summarize the basic p …

Coleen A. McNamara, MD Professor of Medicine / Cardiovascular Division Beirne B. Carter Professor of Immunology Director, Carter Immunology Center

Child Health Research Center Coleen A. McNamara, MD Professor of Medicine / Cardiovascular Division Beirne B. Carter Professor of Immunology Director, Carter Immunology Center  “B Lymphocyte-Mediated Protection from Obesity-Induced Inflammation” ZOOM MEETING Friday, March 12, 2021 Time 12:00pm – 1:00pm Key messages/learning objectives: To outline the phenotype and function of B cell subtypes in ob …

Jennifer Richardson Charlton, MD, MSc Associate Professor UVA Department of Pediatrics, Pediatric Nephrology

Child Health Research Center Jennifer Richardson Charlton, MD, MSc Associate Professor UVA Department of Pediatrics, Pediatric Nephrology “ Nephron Number: The Importance of Development, Determinants, and Diagnostics” ZOOM MEETING Friday, February 26, 2021 Time 12:00pm – 1:00pm Key messages/learning objectives: Understand how nephron number is determined and the natural variation in human nephron …

Stephen S. Rich, PhD, FAHA Harrison Professor of Public Health Sciences, UVA Director, Center for Public Health Genomics

Child Health Research Center Stephen S. Rich, PhD, FAHA Harrison Professor of Public Health Sciences, UVA Director, Center for Public Health Genomics “From Bench to Bedside to Community in Type 1 Diabetes” ZOOM MEETING Meeting ID: 936 0435 1581 Passcode: 574068 Friday, February 5, 2021 Time 12:00pm – 1:00pm Key messages/learning objectives: 1. Understand the current evidence for genetics contribut …

Dr. Masako Suzuki, D.V.M., PhD, M.S. Assistant Professor, Computational and Translational Genetics Albert Einstein College of Medicine

    Child Health Research Center Dr. Masako Suzuki, D.V.M., PhD, M.S. Assistant Professor, Computational and Translational Genetics Albert Einstein College of Medicine “Special Seminar, Faculty candidate” “ Long-term Memory of Adverse Prenatal Micronutrient Environment on Offspring” ZOOM MEETING Friday February 12, 2021 Time 12:00pm – 1:00pm   Key messages/learning objectives: Prenatal m …

Hannah Kim, MD “Special Seminar, Faculty candidate” Fellow in Pediatric Nephrology, Johns Hopkins Hospital, Baltimore, M.D.

Child Health Research Center Hannah Kim, MD “Special Seminar, Faculty candidate” Fellow in Pediatric Nephrology, Johns Hopkins Hospital, Baltimore, M.D. “Puberty in Chronic Kidney Disease” ZOOM MEETING Friday January 15, 2021 Time 12:00pm – 1:00pm Key messages/learning objectives: 1. Describe the timing of puberty in children with Chronic Kidney disease 2. Describe factors associated with delayed …

Christine Bakhoum, MD Third Year Pediatric Nephrology Fellow Department Pediatric Nephrology at Rady Children’s Hospital University of California San Diego

Child Health Research Center Special Seminar, Faculty Candidate Christine Bakhoum, MD Third Year Pediatric Nephrology Fellow Department Pediatric Nephrology at Rady Children’s Hospital University of California San Diego “A Constellation of a Problem: Dipper or Non-dipper” ZOOM MEETING Friday, December 11, 2020 Time 12:00pm – 1:00pm Key messages/learning objectives: To describe the relationship of …

Brant E. Isakson, PhD Professor, Molecular Physiology and Biological Physics

Child Health Research Center Brant E. Isakson, PhD Professor, Molecular Physiology and Biological Physics “Endothelial Cell Alpha Hemoglobin in Hypoxia.” ZOOM MEETING Friday December 4, 2020 Time 12:00pm – 1:00pm Key messages/learning objectives:   1) Understand how Alpha Hemoglobin functions in the Blood vessel wall 2) Learn how Alpha Hemoglobin contributes to Arterial function 3) Understand …

Rebecca V. Levy, BM BCh MSc Fellow, Adult & Pediatric Nephrology Montefiore Medical Center, Bronx, NY

Child Health Research Center “Special Seminar, Faculty candidate” Rebecca V. Levy, BM BCh MSc Fellow, Adult & Pediatric Nephrology Montefiore Medical Center, Bronx, NY   “New Frontiers in the Genetics of Chronic Kidney Disease.” ZOOM MEETING Friday, November 20, 2020 Time 12:00pm – 1:00pm Key messages/learning objectives: Review recent literature in the Genetics of Chronic Kidney Disease Ident …

John Bushweller, PhD Professor, Molecular Physiology and Biological Physics Chemistry

Child Health Research Center John Bushweller, PhD Professor, Molecular Physiology and Biological Physics Chemistry “Decoding and Drugging Transcription Factor Fusion Drivers in Leukemia” ZOOM MEETING Friday, November 13, 2020 Time 12:00pm – 1:00pm Key messages/learning objectives: Role of transcription factor fusions as drivers in leukemia Mechanism of MLL-AF9 fusion in leukemia Drug development t …

Vladimir T. Todorov, MD, PhD Head of Experimental Nephrology, Division of Nephrology & Department of Medicine III University Hospital Carl Gustav Carus, Dresden Germany

  All currently scheduled 2020 CHRC Seminar guest speakers:   Talk Titles or TBD   11/13/2020  John Bushweller, Professor, Molecular Physiology and Biological Physics 11/20/2020 Rebecca V. Levy, BM BCh MSc (Research Fellow, Adult & Pediatric Nephrology Montefiore Medical Center, Bronx, NY) 12/04/2020 Brant Isakson, Primary Appointment Professor, Molecular Physiology and Biological Physics …

Imre Noth, MD Division of Pulmonary and Critical Care Medicine

Child Health Research Center Imre Noth, MD Division of Pulmonary and Critical Care Medicine “The Genetics and Pharmacogenomics of Idiopathic Pulmonary Fibrosis: The role of TOLLIP” ZOOM MEETING Friday, October 16th, 2020 Time 12:00-1:00 Learning Objectives: Understand what Idiopathic Pulmonary Fibrosis is, The genetic underpinnings to Idiopathic Pulmonary Fibrosis Potential personalized and precis …

Alexander Kula, MD, MHS Senior Pediatric Nephrology Fellow Seattle Children’s Hospital, University of Washington

Child Health Research Center   Alexander Kula, MD, MHS Senior Pediatric Nephrology Fellow Seattle Children’s Hospital, University of Washington “A Delicate Balance:  The Kidney and Heart, in Health and Disease”  ZOOM MEETING Friday, October 9, 2020 Time 12:00pm – 1:00pm Disclosures; Speaker: Dr. Alexander Kula has no personal or professional financial relationships with commercial entities produci …

Mark D. DeBoer, MD Associate Professor, Pediatric Endocrinology

Daniel W. Lee, M.D. Assistant Professor Director Pediatric Hematopoietic Stem Cell Transplantation & Immunotherapy Division of Pediatric Hematology/Oncology

Steven L. Zeichner, MD, PhD McLemore Birdsong Professor Departments of Pediatrics & Microbiology, Immunology, and Cancer Biology Director Pendleton Pediatric Infectious Disease Laboratory

CHRC Grant Review Sessions

Child Health Research Center CHRC Grant Review Sessions   Dear Faculty, Students, and Postdocs, We hope you and your family are all doing well and stay safe. This is to let you know that we will soon re-start our Grant Review Sessions on Fridays at noon. If you are considering submitting a grant proposal, we would like to offer you the opportunity to have your specific aims reviewed by members of …

Brian A. Nosek, PhD Executive Director Center for Open Science Professor, Department of Psychology University of Virginia

Child Health Research Center Brian A. Nosek, PhD Executive Director Center for Open Science Professor, Department of Psychology University of Virginia   “Shifting incentives from getting it published to getting it right”   Friday, March 6th, 2020 12:00 – 1:00 pm (lunch at 11:45)* ERC Room B *Free lunch served on a first-come basis starting at 11:45 a.m.   Disclosures: Speaker: Dr. Nosek …

P. Todd Stukenberg, PhD Professor, Biochemistry and Molecular Genetics

Child Health Research Center Todd Stukenberg, PhD Professor, Biochemistry and Molecular Genetics “The misregulation of a non-membranous organelle on mitotic chromosomes generates aneuploidy in breast cancers.”   Friday, February 21st, 2020 12:00 – 1:00 pm (lunch at 11:45)* Battle Bldg. Quayle Learning Center *Free lunch served on a first-come basis starting at 11:45 a.m.              Disclosu …

W. Gerald Teague, MD Ivy Foundation Professor of Pediatrics, Associate Director, Child Health Research Center Clinical Studies

Child Health Research Center Gerald Teague, MD Ivy Foundation Professor of Pediatrics, Associate Director, Child Health Research Center Clinical Studies “Spatial Inhomogeneity of Ventilation as Resolved by Hyperpolarized Noble Gas MR in Childhood Asthma: Necessary and Sufficient”  Friday, 14th, 2020 12:00 – 1:00 pm (lunch at 11:45)* Battle Bldg. Quayle Learning Center *Free lunch served on a first …

Dr. Francine Evalina Garrett-Bakelman Assistant Professor, Biochemistry and Molecular Genetics

Child Health Research Center  Dr. Francine Evalina Garrett-Bakelman Assistant Professor, Biochemistry and Molecular Genetics  “Genomic and Epigenomic events in high risk Acute Myeloid Leukemia” Friday, January 24th, 2020 12:00 – 1:00 pm (lunch at 11:45)* Battle Bldg. Quayle Learning Center *Free lunch served on a first-come basis starting at 11:45 a.m.   Disclosures: Speaker: Dr. Francine Evalina …

William Petri, MD, PhD Vice Chair for Research, Department of Medicine, Wade Hampton Frost Professor of Epidemiology, University of Virginia

Child Health Research Center William Petri, MD, PhD Vice Chair for Research, Department of Medicine, Wade Hampton Frost Professor of Epidemiology, University of Virginia “Enteric infection and inflammation and impact on infant neurodevelopment in Bangladesh” Friday, December 20th, 2019 12:00 – 1:00 pm (lunch at 11:45)* Battle Bldg. Quayle Learning Center *Free lunch served on a first-come basis st …

Ellen Grant, MD Professor of Radiology and Pediatrics Harvard Medical School, Director of Fetal and Neonatal Neuroimaging Research, Endowed Chair in Neonatology Boston Children’s Hospital

Child Health Research Center Ellen Grant, MD Professor of Radiology and Pediatrics Harvard Medical School Director of Fetal and Neonatal Neuroimaging Research Endowed Chair in Neonatology Boston Children’s Hospital “Novel Approaches to Fetal and Neonatal Monitoring” Friday, November 8, 2019 12:00 – 1:00 pm (lunch at 11:45)* Battle Bldg. Quayle Learning Center *Free lunch served on a first-come bas …

Christian Hugo, Prof. Dr. Med Department Head of Nephrology and Kidney Center, Dresden University, Germany, Secretary-General of the German Transplantation Society

Child Health Research Center Christian Hugo, Prof. Dr. Med Department Head of Nephrology and Kidney Center, Dresden University, Germany, Secretary-General of the German Transplantation Society “The juxtaglomerular apparatus: A renin lineage precursor cell niche for glomerular regeneration” Friday, November 1st, 2019 12:00 – 1:00 pm (lunch at 11:45)* Battle Bldg. Quayle Learning Center *Free lunch …

Rachel Moon, MD Harrison Distinguished Teaching Professor of Pediatrics, Division Chief, General Pediatrics

Child Health Research Center Rachel Moon, MD Harrison Distinguished Teaching Professor of Pediatrics Division Chief, General Pediatrics “The importance of social networks, social norms, and attitudes in infant care practice decisions” Friday, October 25, 2019 12:00 – 1:00 pm (lunch at 11:45)* Battle Bldg. Quayle Learning Center *Free lunch served on a first-come basis starting at 11:45 a.m. Disclo …

Christopher Wilcox, M.D., Ph.D., F.R.C.P., F.A.C.P.

Child Health Research Center Christopher Wilcox, M.D., Ph.D., F.R.C.P., F.A.C.P. Professor, Department of Medicine Chief, Division of Nephrology and Hypertension Director, Center for Hypertension, Kidney, and Vascular Health Georgetown University   “Resilience of cerebral arterioles to vasoconstriction protects the brain from vascular dementia and stroke”   October, 11, 2019 12:00 – 1:00 pm (lunch …

CHRC: A Lecture to Honor the Contributions of Dr. Peter Heymann to the Understanding of Childhood Asthma

Child Health Research Center A Lecture to Honor the Contributions of Dr. Peter Heymann to the Understanding of Childhood Asthma “Rhinovirus-induced Dysmaturation of the Airway Epithelium Stimulates Type II Inflammatory Signatures in Preschool Children with Severe Wheeze” Lecturer: W. Gerald Teague, MD Ivy Foundation Distinguished Professor of Pediatrics Associate Director, Child Health Research Ce …

CHRC Speaker Series: Jeffrey Toretsky, MD

Child Health Research Center Jeffrey Toretsky, MD Professor of Oncology and Pediatrics, Georgetown University    “From Idea on a Napkin to Clinical Trial: Creating a Drug for a Rare Cancer”  Friday, September 27, 2019 12:00 – 1:00 pm (lunch at 11:45)* Battle Bldg. Quayle Learning Center *Free lunch served on a first-come basis starting at 11:45 a.m.               Disclosures: Speaker: Dr. Toretsky …

Epigenetic and Proliferative Mechanisms of Renin Cell Plasticity

Omar Guessoum1, Maria Luisa S. Sequeira-Lopez2, Ariel Gomez1,2 1 Department of Biology, University of Virginia, Charlottesville, VA 2 Department of Pediatrics, Division of Nephrology, University of Virginia School of Medicine. Mentors: Ariel Gomez & Maria Luisa Sequeira-Lopez, Department of Pediatrics, Division of Nephrology. Background: The Renin-Angiotensin-System (RAS) is essential to maint …

K23 NIH Mentored Patient-Oriented Research Career Development Award

Sana Syed, MD, MS It gives us great pleasure to announce that Dr. Syed received her K23 NIH Mentored Patient-Oriented Research Career Development Award (starting fall 2019) focused on computational image analysis and ‘omics approaches to study gut structure in children with undernutrition (environmental enteropathy and celiac disease). This award is presented to individuals with an intensive, supe …

First person – Brian Belyea, MD

©2018. Published by The Company of Biologists Ltd I Disease Models & Mechanisms (2018) 11. dmm038463. doi:10.1242/dmm.038463 First Person is a series of interviews with the first authors of a selection of papers published in Disease Models & Mechanisms. helping early-career researchers promote themselves alongside their papers. Brian Belyea is first author on ‘Leukemia development initiate …

CHRC Speaker Series: Asad Ali, MD, MPH

Child Health Research Center Speaker Series Asad Ali, MD, MPH  Associate Dean, Research, Aga Khan University Associate Professor, Department of Pediatrics and Child Health Director Research, Department of Pediatrics & Child Health   “Chronic malnutrition and its impact on child health: Lessons from the field”   Friday, May 10, 2019 12:00 – 1:00 pm (lunch at 11:45)* Battle Bldg. Quayle Lea …

CHRC Speaker Series: Richard Guerrant, MD

Child Health Research Center Speaker Series Richard Guerrant, MD Thomas Harrison Hunter Professor of International Medicine: Infectious Diseases and International Health University of Virginia “The Costly lifelong triple burden of early childhood enteric infections (HAZdrop, COGhit & METsyn): bridging clinical & lab research” Friday, April 5th, 2019 12:00 – 1:00 pm (lunch at 11:45)* Battle …

CHRC Speaker Series: Benjamin Purow, MD

Child Health Research Center Speaker Series Benjamin Purow, MD  Professor of Neurology, Neuroscience, Medicine, Pediatrics, and Biochemistry and Molecular Genetics University of Virginia “Bypassing brain tumor defenses with targeted and immunotherapy strategies”   Friday, March 22nd, 2019 12:00 – 1:00 pm (lunch at 11:45)* Battle Bldg. Quayle Learning Center *Free lunch served on a first-come basis …

31st Annual Research Symposium

Children’s Health Research Center Presents the 31st Annual Research Symposium Thursday, May 30th Call for Abstracts: ABSTRACT DUE DATE – Friday, April 12, 2019 The Research Trainee Competition features Platform Presentations by Residents, Medical Fellows, Medical Students, Graduate Students and Undergraduates. Trainees of any member of the Dept. of Pediatrics or associated to the CHRC are encourag …

3rd Annual Betsy and Stuart Houston Lecture

CHILD HEALTH RESEARCH CENTER  PRESENTS The Betsy and Stuart Houston Lecture     Klaus Rajewsky, M.D. Professor & Senior Group Leader Immune Regulation & Cancer, Max Delbrück Centrum für Molekulare Medizin, Berlin­Buch, Germany   “Targeted mutagenesis and gene repair in modeling and controlling human lymphoid disorders” Wednesday, November 7, 2018 4 PM Claude Moore Medical Educati …

2018 Maddy Deal Grant Recipients

Let’s congratulate our recent Maddy Deal recipients for 2018 Dr. Rebecca Scharf for “Novel Systems to Assess Treatment Efficacy in Childhood Neuromuscular Disease.” The goal of this research is to find a novel, multi-model paradigm of measuring motor function in children with Spinal Muscular Atrophy. Currently, outcome measures are imprecise and much time is needed to see changes. We seek to creat …

30th Annual Research Symposium

The PCEN in conjunction with the CHRC sponsored and organized the 30th Annual Research Day Symposium that took place at UVA on May 31th 2018. This symposium offered an outstanding presentation of Pediatrics’ trainees and faculty mentors’ research. Dr. Norman D. Rosenblum MD, FRCPC (Professor of Pediatrics, Physiology, and Laboratory Medicine and Pathobiology at the University of Toronto, and a Ped …

Dr. Sana Syed Selected for THRIV Scholar Career Development Program

Dr. Sana Syed Congratulations to Dr. Sana Syed one of our own at the Child Health Research Center. She has been selected to be part of the THRIV Scholar Career Development Program.  Every year the Translational Health Research Institute of Virginia (THRIV) chooses up to 5 candidates to be a part of the two-year Career Development program. Dr. Syed’s project focuses on the development of an image a …

Public Health Challenge | Severe Asthma

29th Annual Research Symposium

<►> Our 29th Annual Research Symposium took place on Thursday, May 27, 2017. The research day offers an excellent opportunity for faculty and staff of the CHRC to present the ground-breaking research that they undertake. Following the poster presentations, the trainee competition awards were given to Corrie Alonzo, Florencia Martinez and Sarah Miller for their outstanding work this pas …

Dr. Ariel Gomez Received A Distinguished Alumni Award

CHRC director, Dr. R. Ariel Gomez was recently awarded the 2017 Distinguished Alumni Award for Achievement by the University of Iowa Carver College Medical Alumni Association. The award was established in 1998 as the highest honor bestowed upon graduates of the institution. The Alumni Award for Achievement in particular is given to a deserving candidate who exhibits “significant professional accom …

2017 Betsy and Stuart Houston Lecture | Hans Clevers, M.D., Ph.D.

The University of Virginia was honored to have Johannes Carolus (Hans) Clevers, a professor in molecular genetics, a geneticist, physician, and medical researcher, present the second annual Betsy and Stuart Houston Lecture, on April 27, 2017. His lecture attracted many and was very well attended, as the entire Medical Education Building Auditorium was full. In addition, a live airing was available …

Discovery About How Heart Forms Sheds Light on Deadly Disease

Drs. Maria Luisa Sequeira-Lopez, Yan Hu and Brian Belyea were recently featured in a UVA Today article

Fate of Renin Cells During Development

Rhian Touyz, MD, PhD interviews Ariel Gomez, MD, corecipient of the 2016 Excellence in Hypertension Award about his research into the fate of renin cells during development and disease. https://www.youtube.com/watch?v=U2kOpXw2a2s  

Probing the Secrets of Cell Identity

Dr. Ariel Gomez’s research was recently featured in a UVA Today article.

Congratulations to Masafumi Oka, MD and Vidya Kusma Harinathan, PhD!

Congratulations to Masafumi Oka, MD and Vidya Kusma Harinathan, PhD, who were both selected to receive the Kidney Council New Investigator Travel Award. This award will be presented to them at the Annual Business Meeting/Awards luncheon of the 2016 Council on Hypertension on Friday, September 16 in Orlando, Florida.

28th Annual Research Symposium

<►> Our 28th Annual Research Day Symposium offered an outstanding presentation of the scholarly assembly of Pediatrics’ trainees and faculty mentors’ research. The day commenced with an excellent presentation by our keynote speaker, Alessio Fasano, MD, W. Allan Walker Chair of Pediatric Gastroenterology and Nutrition at Mass General Hospital for Children. The poster session was held in …

Congratulations to the 2016 Research Trainee Competition Winners!

Congratulations to our Winners! 2016 Kendig Award Winner  The 2016 Kendig Award goes to Matthew Harer. Research Trainee Competition Winners Maria Florencia Martinez |  Super-Enhancers in the renin cell Erika Rhone | Genomic-derived markers to identify calcineurin inhibitor nephrotoxicity in pediatric kidney transplant recipients Sarah Miller | Low birth weight associated with poor executive functi …

Jennifer Charlton, MD Recieves ASN Research Grant

Jennifer Charlton, MD Jennifer Charlton, MD recently recieved the Carl W. Gottschalk Research Scholar Grant from the American Society of Nephrology. The purpose of the Carl W. Gottschalk Research Scholar Grant is to provide funding for young faculty to foster evolution to an independent research career by providing transition funding toward successful application for an RO1 grant.

2016 Betsy and Stuart Houston Lecture | Mario Capecchi, PhD

Mario R. Capecchi, PhD, a Nobel Laureate whose work can be applied either directly or indirectly to nearly every medical field of research, spoke at the University Tuesday. Capecchi, with Sir Martin J. Evans and Oliver Smithies, received the 2007 Nobel Prize in Physiology or Medicine for their research on the use of embryonic stem cells to introduce gene modifications in mice. His lecture filled t …

Brian C. Belyea, MD | 2016 Young Physician-Scientist Award Winner

Congratulations to Dr. Belyea who was recently selected by the The American Society for Clinical Investigation for the Young Physician-Scientist Award of 2016. The ASCI Council Young Physician-Scientist Awards, initiated in 2013, recognize young physician-scientists who are supported by NIH K awards or similar significant career-development awards, are early in their first faculty appointment, and …

NIH K Award Symposium Outstanding Investigator Award | Jennifer Charlton, MD

Jennifer Charlton, MD was recently awarded the Outstanding Investigator Award at the NIH K Award Symposium for her work, “Chronic Kidney Disease: Early Diagnosis by Contrast-Enhanced MRI”. The Department of Medicine’s K-awardee mentoring program, launched by DoM Vice Chair for Research Eric Houpt, MD, hosts regular meetings of this cohort to provide support, guidance, and opportunities for network …

Congratulations, Dr. Maria Luisa Sequeria Lopez!

Congrats to Dr. Maria Luisa Sequeira Lopez for her elected position as the next vice chair and subsequently the new Chair of the Angiotensin Gordon Research Conference  

Gap Funding Award | An Interview with Santina A. Zanelli, MD

Project name Role of kainate receptors on modulation of synaptic transmission and seizure susceptibility to hypoxia in neonatal mice Gap funding award $50,000. Time frame One year Q: Please describe your project. Seizures in neonates are a vexing clinical problem with lack of consensus on diagnosis and management. The problem is further compounded by the disappointing efficacy of currently availab …

Congrats, Jorge Giron and Julia Wisniewski!

Congratulations to the winners of the Innovative Grants! The titles of the grants were “Adhesins of Stenotrophomonas maltophilia, a health burden in cystic fibrosis patients” (Jorge Giron) and “Influence of detergent skin cleanser use on Development of Atopic disease in Children” (Julia Wisniewski). We are proud of you! Jorge Giron, PhD Julia Wisniewski, MD

UVA Discovery a Major Step Toward Growing Kidneys

UVA Today recently featured an article about some of our CHRC research staff. In a significant step toward growing replacement kidneys, researchers at the University of Virginia School of Medicine have identified the cells that give rise to the blood vessels within the kidney. It’s a discovery of critical importance, as efforts to grow kidneys have long been frustrated by the inability to create t …

CHRC Featured in Fall PULSE Issue

PULSE – Philanthropy in Action, a newsletter focusing on new programs, gifts, volunteers, needs, and other timely issues at the UVA Health System, ran a story in it’s most recent bi-annual publication featuring the Child Health Research Center. The story highlights the establishment of the CHRC Speaker Series. Each entry, as well as past archives, of the speaker series can be accessed by the bar t …

Dr. Ariel Gomez is awarded the UVA Distinguished Scientist Award.

R. Ariel Gomez, MD On November 11, 2015 Dr. Ariel Gomez, along with Dr. Anindya Dutta, Dr. Doug Bayliss, and Dr. Jack Stankovic,  was honored with the University of Virginia Distinguished Scientist Award during an award dinner held at The Colonade Club in Charlottesville. The UVA Distinguished Scientist Award, founded in 2006, recognizes faculty from the basic, medical, or engineering sciences who …

Innovative Science and Excellence in Pediatric Research Grant

General Information: The Child Health Research Center is searching to fund innovative, paradigm shifting, and/or technology advancing projects through an Innovative Science and Excellence in Pediatric Research Grant.  Funding will support projects in basic, translational, and/or clinical research to obtain preliminary data for external funding. Amount: $12,500: One grant for Young Investigators ( …

Maddy Deal Pilot Project Grant Awarded to Vidya Kusma Harinathan, PhD

Please join us to congratulate Vidya Kusma Harinathan, PhD, Instructor of Research, Pediatrics! She is the winner of the 2015 Maddy Deal Pilot Project Grant entitled “Membrane Immunoassay for Detecting Single cell Renin Secretion.” Please congratulate Vidya! We are very proud of her!

CHRC Speaker Series: Carlos Bernal-Mizrachi, MD

The Child Health Research Center Presents: Hypertension and inflammation: unexpected communication between innate immunity and juxtaglomerular cells Carlos Bernal-Mizrachi, MD Associate Professor of Medicine, Cell Biology and Physiology Division of Endocrinology, Metabolism & Lipid Research Washington University Friday, March 8th, 2019 12:00 – 1:00 pm (lunch at 11:45)* Battle Bldg. Quayle Lear …

Congrats, Eugene Lin and Yan Hu!

Please join us to congratulate our graduate students who won basic research awards at the 2015 Mid-Atlantic Young Investigators Fo
rum, held at the Renaissance Hotel in Baltimore, MD. This event allows trainees from Mid-Atlantic research programs to present their basic and clinical research on kidney diseases. Eugene Lin (1st place) (mentors: Ariel Gomez, Maria Luisa Sequeira Lopez) Yan Hu (5th pl …