Date: Friday April 3, 2015
Time: 9:00 AM until 10:00 AM
Location: MR4 Building, 3rd floor conference room
Dr. Hiroko Nishimura has made many original contributions to our understanding of the neuro-humoral mechanisms regulating blood pressure and kidney function, and the pathophysiology of diseases such as hypertension and atherosclerosis. Her innovative use of comparative physiology approaches and unique animal models has elucidated evolutionary aspects of biological functions that have broad impact on our understanding of human physiology and diseases. In particular, she has been known for her research on: 1) evolution of the renin-angiotensin system and angiotensin receptors and their fundamental role in blood pressure regulation, 2) vasodepressor action of angiotensin via nitric oxide and K channels, 3) vascular injury and atherosclerotic lesions by high blood pressure, 4) evolution of counter-current urine concentration mechanisms and aquaporins, and 5) developmental origins of glomerulosclerosis.
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