Mission & Goals

The mission of the Center is two fold. First, to unite the research efforts within University of Virginia on the topic of apoptotic cell clearance through effective communication of ongoing research and better sharing of ideas and reagents such that the collective efforts make better advances than the isolated efforts of individual investigators.Second, the Center for Cell Clearance aims to link investigators from around the world through a common website run through this Center, and thereby foster better intellectual exchange and overall progress in the field of apoptotic cell clearance.

The goals of the CCC are: (i) to integrate and enhance the research efforts on apoptotic cell clearance within the University of Virginia, and (ii) to provide a forum for investigators from around the world to seek information, reagents and advice from others working in the field, and to foster collaborations.

Short Term Goals (0-3 Years)

·    Facilitate better coordination of the ongoing efforts within University of Virginia and initiate new collaborative avenues of investigation

·    Hiring new faculty and fully establishing the Center for Cell Clearance

·    Creation of the CCC website useful for all investigators (inside and outside UVA) to allow the exchange of ideas, reagents and advice within the engulfment community

·    Generation of new mouse lines useful for studies of engulfment

·    Provide a better intellectual exchange between students, post-docs and faculty working on apoptotic cell clearance

·    Applying for collaborative grant funding

Long Term Goals (0-5 Years)

·    Provide a mouse repository resource for knockout and transgenic mice for the various engulfment genes that can be acquired by all investigators in the field of apoptotic cell clearance

·    Using input from the various investigators within and outside UVA, continually improve the mechanism(s) of intellectual and reagent exchange between investigators in the field of apoptotic cell clearance

·    Expand the usefulness, visibility and resources of the CCC through acquisition of additional collaborative grant funding and Center grants